Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.60 |
| ▸ | PPARG | P37231 | 3/20 | 0.57 |
| ▸ | PPARD | Q03181 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439234 | 0.84 | NR1H4 (0.56) | HPGDMAPK14HTTSMN1; SMN2MMP13 | |
| SCHEMBL25044550 | 0.81 | SMN1; SMN2 (0.74) | HPGDHTTSMN1; SMN2LMNACYP3A4 | |
| SCHEMBL22647188 | 0.81 | MAPK14 (0.60) | HPGDMAPK14PPARGPPARDPPARA | |
| SCHEMBL2910477 | 0.79 | LMNA (0.59) | SMN1; SMN2MMP13LMNA | |
| SCHEMBL8738321 | 0.79 | MAPK14 (0.76) | HPGDMAPK14HTTSMN1; SMN2MMP13 | |
| SCHEMBL12391553 | 0.79 | HTT (0.59) | HPGDHTTSMN1; SMN2LMNACYP3A4 | |
| SCHEMBL16658357 | 0.79 | HPGD (0.69) | HPGDHTTSMN1; SMN2LMNACYP3A4 | |
| SCHEMBL18382971 | 0.79 | HTT (0.59) | HPGDHTTSMN1; SMN2LMNACYP3A4 | |
| SCHEMBL25045867 | 0.79 | HPGD (0.60) | HPGDHTTSMN1; SMN2LMNACYP3A4 | |
| SCHEMBL8738317 | 0.78 | HPGD (0.97) | HPGDMAPK14PPARGPPARAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140186-A1 | A PROCESS FOR PREPARING 5-PHENOXY-1(3H)ISOBENZOFURANONE | KINGCHEM LIFE SCIENCE LLC (US) | 2018-08-02 | — | — | WO | disclosed |