Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48365 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1TAAR1SLC6A2 | |
| SCHEMBL30678520 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1TAAR1SLC6A2 | |
| SCHEMBL2868262 | 0.87 | TSHR (0.43) | ALDH1A1TSHRTDP1TAAR1SLC6A2 | |
| SCHEMBL20439254 | 0.79 | TDP1 (0.50) | ALDH1A1TSHRTDP1TAAR1SLC6A2 | |
| SCHEMBL18364918 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1CA2 | |
| SCHEMBL23862430 | 0.75 | CA2 (0.37) | ALDH1A1TSHRTDP1CA2 | |
| SCHEMBL4500149 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TSHRTDP1 | |
| SCHEMBL26725213 | 0.75 | CYP3A4 (0.43) | ALDH1A1TSHRTDP1CA2 | |
| SCHEMBL29581427 | 0.72 | TSHR (0.45) | ALDH1A1TSHRTDP1TAAR1SLC6A2 | |
| SCHEMBL164361 | 0.72 | TSHR (0.45) | ALDH1A1TSHRTDP1TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180216107-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2018-08-02 | — | — | US | disclosed |