Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425155 | 1.00 | ESR1 (0.45) | ESR1FPR2PROKR1CCR1KDM4E | |
| SCHEMBL20439452 | 0.80 | FPR2 (0.53) | FPR2PROKR1 | |
| SCHEMBL20439312 | 0.76 | SLC6A4 (0.61) | FPR2PROKR1 | |
| SCHEMBL31249052 | 0.74 | SLC6A2 (0.39) | FPR2 | |
| SCHEMBL31697091 | 0.73 | FPR2 (0.49) | FPR2PROKR1 | |
| SCHEMBL16695161 | 0.73 | FPR2 (0.49) | FPR2PROKR1 | |
| SCHEMBL20165272 | 0.73 | HMOX1 (0.44) | ESR1CCR1 | |
| SCHEMBL20165275 | 0.73 | HMOX1 (0.44) | ESR1CCR1 | |
| SCHEMBL20425163 | 0.72 | FPR2 (0.46) | FPR2PROKR1KDM4E | |
| SCHEMBL23529265 | 0.72 | CHRM2 (0.58) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |