Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.53 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | HTR2B | P41595 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13419295 | 0.84 | HTR2C (0.55) | FPR2PROKR1HTR2CHTR2BSLC6A4 | |
| SCHEMBL13419691 | 0.82 | HTR2C (0.50) | HTR2CHTR2BSLC6A4HTR6UTS2R | |
| SCHEMBL30820568 | 0.82 | NOS3 (0.45) | HTR2CHTR2BSLC6A4HTR6UTS2R | |
| SCHEMBL681762 | 0.82 | UTS2R (0.49) | UTS2R | |
| SCHEMBL872104 | 0.82 | UTS2R (0.49) | UTS2R | |
| SCHEMBL24714032 | 0.82 | NOS3 (0.45) | HTR2CHTR2BSLC6A4HTR6UTS2R | |
| SCHEMBL873202 | 0.82 | UTS2R (0.49) | UTS2R | |
| SCHEMBL16695161 | 0.81 | FPR2 (0.49) | FPR2PROKR1SLC6A4HTR6 | |
| SCHEMBL31697091 | 0.81 | FPR2 (0.49) | FPR2PROKR1SLC6A4HTR6 | |
| SCHEMBL20439354 | 0.80 | ESR1 (0.45) | FPR2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |