Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 4/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31734716 | 0.89 | KMT2A (0.52) | KMT2AEPHX2CASP3MDM4TP53 | |
| SCHEMBL31121697 | 0.89 | KMT2A (0.52) | KMT2AEPHX2CASP3MDM4TP53 | |
| SCHEMBL29929040 | 0.89 | KMT2A (0.52) | KMT2AEPHX2CASP3MDM4TP53 | |
| SCHEMBL6507736 | 0.89 | KMT2A (0.52) | KMT2AEPHX2CASP3MDM4TP53 | |
| SCHEMBL6629894 | 0.89 | KMT2A (0.52) | KMT2AEPHX2CASP3MDM4TP53 | |
| SCHEMBL6854697 | 0.87 | CASP3 (0.50) | KMT2AEPHX2CASP3MDM4TP53 | |
| SCHEMBL1827314 | 0.85 | CASP3 (0.51) | KMT2AEPHX2CASP3MDM4TP53 | |
| SCHEMBL14951948 | 0.84 | KMT2A (0.45) | KMT2AEPHX2CASP3MDM4TP53 | |
| SCHEMBL3580924 | 0.82 | CASP3 (0.50) | KMT2ACASP3MDM4TP53 | |
| SCHEMBL7984402 | 0.81 | MDM4 (0.52) | KMT2AEPHX2CASP3MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |