Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ACACB | O00763 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439387 | 0.85 | BCL2 (0.50) | LMNAL3MBTL1ACACBALOX5GPR88 | |
| SCHEMBL20425274 | 0.85 | BCL2 (0.50) | LMNAL3MBTL1ACACBALOX5GPR88 | |
| SCHEMBL13380235 | 0.79 | KEAP1 (0.50) | LMNAGPR88 | |
| SCHEMBL1952124 | 0.79 | KEAP1 (0.50) | LMNAGPR88 | |
| SCHEMBL18766237 | 0.79 | KEAP1 (0.50) | LMNAGPR88 | |
| SCHEMBL16965686 | 0.79 | KEAP1 (0.50) | LMNAGPR88 | |
| SCHEMBL1443078 | 0.78 | KMT2A (0.47) | L3MBTL1ACACBGPR88RAB9A | |
| SCHEMBL20425198 | 0.78 | PRKCA (0.54) | ACACBGPR88MAOB | |
| SCHEMBL16541091 | 0.78 | SIGMAR1 (0.60) | LMNAL3MBTL1ACACBLTA4HMAOB | |
| SCHEMBL1497960 | 0.78 | LMNA (0.61) | LMNAL3MBTL1ALOX5MAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |