Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.33 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.33 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439439 | 0.89 | CYP4F2 (0.41) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL20439391 | 0.88 | RXRA (0.39) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL20439389 | 0.88 | RXRA (0.39) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL680099 | 0.82 | RXRA (0.49) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL20439382 | 0.73 | CYP4F2 (0.41) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL22836590 | 0.72 | RXRA (0.46) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL25417935 | 0.71 | RXRA (0.46) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL31704480 | 0.71 | RXRA (0.46) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL680602 | 0.71 | ATR (0.47) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL20590847 | 0.71 | CYP4F2 (0.57) | CYP4F2CYP4A11RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |