Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14416003 | 0.89 | MAPK13 (0.33) | KCNH2 | |
| SCHEMBL15996487 | 0.83 | ADORA2A (0.33) | KCNH2ADORA2B | |
| SCHEMBL10036618 | 0.79 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL10233671 | 0.79 | — | — | |
| SCHEMBL14465623 | 0.77 | CYP2C9 (0.35) | ADORA2B | |
| SCHEMBL26773832 | 0.77 | IDO1 (0.48) | KCNH2 | |
| SCHEMBL1178679 | 0.75 | — | — | |
| SCHEMBL17544717 | 0.74 | CPB1 (0.30) | — | |
| Bromide SCHEMBL6369678 | 0.73 | CYP19A1 (0.41) | — | |
| SCHEMBL6180585 | 0.73 | CYP11B1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138088-A1 | BICYCLIC BIS-HETEROARYL DERIVATIVES AS MODULATORS OF PROTEIN AGGREGATION | UCB BIOPHARMA SPRL (BE) | 2018-08-02 | — | — | WO | disclosed |