Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442635 | 0.85 | PTGER4 (0.39) | IDO1PTGER4KDM4EGAAMAPT | |
| SCHEMBL16831571 | 0.85 | PTGER4 (0.39) | IDO1PTGER4KDM4EGAAMAPT | |
| SCHEMBL28855491 | 0.84 | PTGER4 (0.36) | PTGER4KDM4EGAAMAPTPKM | |
| SCHEMBL20797368 | 0.82 | PTGER4 (0.36) | PTGER4GAAMAPTNPC1ALDH1A1 | |
| SCHEMBL30620286 | 0.81 | NCF1 (0.40) | PTGER4ALDH1A1HTT | |
| SCHEMBL22032134 | 0.81 | CYP19A1 (0.40) | PTGER4KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL22032153 | 0.80 | ALDH1A1 (0.41) | PTGER4KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL31162829 | 0.79 | ALDH1A1 (0.40) | PTGER4KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL30620316 | 0.78 | MAPT (0.34) | PTGER4MAPTPKMPOLB | |
| SCHEMBL28855533 | 0.77 | KCNH3 (0.35) | PTGER4KDM4EGAAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140876-A1 | NRF2 ACTIVATOR | BIOGEN MA INC. (US) | 2018-08-02 | — | — | WO | disclosed |