Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA3 | P07451 | 3/20 | 0.35 |
| ▸ | CA6 | P23280 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MIF | P14174 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8187989 | 0.90 | ATM (0.37) | MAOBKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL8187218 | 0.68 | MEN1 (0.41) | MAOBKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL2060555 | 0.65 | SIRT6 (0.40) | ALDH1A1HPGDMAPTLMNATP53 | |
| SCHEMBL9672632 | 0.65 | MAOB (0.56) | MAOBKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL2060564 | 0.63 | CHRM1 (0.43) | ALDH1A1 | |
| SCHEMBL9802734 | 0.62 | MAOB (0.45) | MAOBKDM4EALDH1A1HPGDCA12 | |
| Malonic Acid Diethyl Ester SCHEMBL29093543 | 0.61 | KDM4E (0.78) | MAOBKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL8163031 | 0.60 | KDM4E (0.51) | MAOBKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL8196361 | 0.59 | ALDH1A1 (0.46) | MAOBKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL13045376 | 0.58 | ALDH1A1 (0.40) | KDM4EALDH1A1GAAMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140876-A1 | NRF2 ACTIVATOR | BIOGEN MA INC. (US) | 2018-08-02 | — | — | WO | disclosed |