Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425572 | 0.88 | FAAH (0.39) | MAOAMAOBFAAHMEN1KMT2A | |
| SCHEMBL20425597 | 0.88 | FAAH (0.39) | MAOAMAOBFAAHMEN1KMT2A | |
| SCHEMBL20439779 | 0.88 | FAAH (0.39) | MAOAMAOBFAAHMEN1KMT2A | |
| SCHEMBL20425617 | 0.88 | FAAH (0.39) | MAOAMAOBFAAHMEN1KMT2A | |
| SCHEMBL20439624 | 0.68 | KMT2A (0.48) | MEN1KMT2AALDH1A1LMNAABCG2 | |
| SCHEMBL20439674 | 0.66 | SMN1; SMN2 (0.37) | KMT2AHCRTR2LMNAOPRM1OPRD1 | |
| SCHEMBL20425562 | 0.66 | SMN1; SMN2 (0.37) | KMT2AHCRTR2LMNAOPRM1OPRD1 | |
| SCHEMBL29551110 | 0.66 | HSD17B3 (0.46) | MEN1KMT2AL3MBTL1TP53ALDH1A1 | |
| SCHEMBL20425850 | 0.66 | HSD17B3 (0.46) | MEN1KMT2AL3MBTL1TP53ALDH1A1 | |
| SCHEMBL20440028 | 0.65 | MGLL (0.40) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140876-A1 | NRF2 ACTIVATOR | BIOGEN MA INC. (US) | 2018-08-02 | — | — | WO | disclosed |