Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 7/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425597 | 1.00 | FAAH (0.39) | FAAHFFAR2L3MBTL3L3MBTL1MAOA | |
| SCHEMBL20425572 | 1.00 | FAAH (0.39) | FAAHFFAR2L3MBTL3L3MBTL1MAOA | |
| SCHEMBL20425617 | 1.00 | FAAH (0.39) | FAAHFFAR2L3MBTL3L3MBTL1MAOA | |
| SCHEMBL20439781 | 0.88 | MAOA (0.38) | FAAHL3MBTL3L3MBTL1MAOAMAOB | |
| SCHEMBL20425562 | 0.77 | SMN1; SMN2 (0.37) | KMT2AOPRM1OPRD1OPRK1HCRTR2 | |
| SCHEMBL20439674 | 0.77 | SMN1; SMN2 (0.37) | KMT2AOPRM1OPRD1OPRK1HCRTR2 | |
| SCHEMBL20425776 | 0.76 | P4HB (0.40) | FFAR2 | |
| SCHEMBL20425643 | 0.76 | OPRM1 (0.40) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL20425598 | 0.76 | MGLL (0.40) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20440028 | 0.76 | MGLL (0.40) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140876-A1 | NRF2 ACTIVATOR | BIOGEN MA INC. (US) | 2018-08-02 | — | — | WO | disclosed |