Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20440162 | 0.83 | NPC1 (0.41) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL4970738 | 0.81 | RAB9A (0.50) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL18735579 | 0.80 | LMNA (0.47) | RAB9ASMN1; SMN2HSD17B10LMNACTSD | |
| SCHEMBL6118223 | 0.79 | NPC1 (0.52) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL15998638 | 0.78 | NPC1 (0.54) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL11696600 | 0.78 | NPC1 (0.55) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL480707 | 0.78 | KDM4E (0.45) | NPC1RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL473974 | 0.77 | HSD17B10 (0.68) | KMT2AMAPTMEN1KDM4EHSD17B10 | |
| SCHEMBL16836022 | 0.77 | HSD17B10 (0.50) | KDM4EHSD17B10AKR1C3CTSDALDH1A1 | |
| SCHEMBL29458589 | 0.77 | HSD17B10 (0.68) | KMT2AMAPTMEN1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3575286-B1 | PYRIDONE COMPOUND AND BACTERICIDE FOR AGRICULTURAL AND HORTICULTURAL USE, WHICH USES SAID COMPOUND AS ACTIVE INGREDIENT | MITSUI CHEMICALS AGRO INC (JP) | 2022-05-11 | — | — | EP | disclosed |
| EP-3575286-B1 | PYRIDONE COMPOUND AND BACTERICIDE FOR AGRICULTURAL AND HORTICULTURAL USE, WHICH USES SAID COMPOUND AS ACTIVE INGREDIENT | MITSUI CHEMICALS AGRO INC (JP) | 2022-05-11 | — | — | EP | disclosed |
| US-11051513-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-07-06 | — | — | US | disclosed |
| US-11051513-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-07-06 | — | — | US | disclosed |
| WO-2018139560-A1 | PYRIDONE COMPOUND AND BACTERICIDE FOR AGRICULTURAL AND HORTICULTURAL USE, WHICH USES SAID COMPOUND AS ACTIVE INGREDIENT | 三井化学アグロ株式会社 | 2018-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11051513-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, PDXK, CBR3 | NPC1 4830/4885RAB9A 4676/4885KMT2A 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.