SCHEMBL204419

SCHEMBL204419

O=C(/C(Cl)=N/O)c1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPT1B Q92523 1/20 0.52
CES2 O00748 2/20 0.50
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
PKM P14618 1/20 0.46
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA12 O43570 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
CA3 P07451 1/20 0.44
TYR P14679 1/20 0.44
DRD1 P21728 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204420 1.00 CPT1B (0.52) CPT1BCES2ESR1ESR2LMNA
SCHEMBL13943817 0.83 CES2 (0.62) CES2LMNAMAPTHTTCA1
SCHEMBL11806648 0.81 CES2 (0.60) CES2LMNAMAPTPKMHPGD
SCHEMBL11806639 0.81 CES2 (0.60) CES2LMNAMAPTPKMHPGD
SCHEMBL11797263 0.81 CES2 (0.60) CES2LMNAMAPTHPGDHTT
SCHEMBL11797258 0.81 CES2 (0.60) CES2LMNAMAPTHPGDHTT
SCHEMBL734683 0.80 CES2 (0.56) CES2LMNAMAPTCA1CA2
SCHEMBL279769 0.80 CES2 (0.56) CES2LMNAMAPTCA1CA2
SCHEMBL11470993 0.77 CPT1B (0.61) CPT1BCES2ESR1ESR2LMNA
SCHEMBL11804994 0.76 HDAC1 (0.48) MAPTHTTCA1CA2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5607544-A PEROXIDATION OF WOOD PULP FOR INK REMOVAL BK Ladenburg GmbH fur Chemische Erzeugnisse (DE) 1997-03-04 US claimed
US-5292945-A Process for preparing α-chloro-α-oximino-4-hydroxyacetophenone HOECHST CELANESE CORPORATION (US) 1994-03-08 US claimed
EP-0545682-A2 Process for preparing alpha-chloro-alpha-oximino-4-hydroxyacetophenone HOECHST CELANESE CORPORATION (US) 1993-06-09 EP claimed
EP-0383539-A1 Production of alpha-chloro-alpha-oximino-4-hydroxy-acetophenone HOECHST CELANESE CORPORATION (US) 1990-08-22 EP claimed
US-4910338-A Production of α-chloro-α-oximino-4-hydroxyacetophenone HOECHST CELANESE CORPORATION (US) 1990-03-20 US claimed
JP-9025205-A None JP disclosed
JP-3083902-A None JP disclosed
JP-7268791-A None JP disclosed
JP-3167101-A None JP disclosed
JP-3170404-A None JP disclosed
JP-5262714-A None JP disclosed
JP-6298607-A None JP disclosed
EP-0383539-A1 Production of alpha-chloro-alpha-oximino-4-hydroxy-acetophenone HOECHST CELANESE CORPORATION (US) 1990-08-22 EP disclosed
EP-0383539-A1 Production of alpha-chloro-alpha-oximino-4-hydroxy-acetophenone HOECHST CELANESE CORPORATION (US) 1990-08-22 EP disclosed
EP-0383539-A1 Production of alpha-chloro-alpha-oximino-4-hydroxy-acetophenone HOECHST CELANESE CORPORATION (US) 1990-08-22 EP disclosed
US-4910338-A Production of α-chloro-α-oximino-4-hydroxyacetophenone HOECHST CELANESE CORPORATION (US) 1990-03-20 US disclosed
US-4910338-A Production of α-chloro-α-oximino-4-hydroxyacetophenone HOECHST CELANESE CORPORATION (US) 1990-03-20 US disclosed
US-4910338-A Production of α-chloro-α-oximino-4-hydroxyacetophenone HOECHST CELANESE CORPORATION (US) 1990-03-20 US disclosed
US-4661518-A SLIMICIDES, BACTERICIDES NALCO CHEMICAL COMPANY (US) 1987-04-28 US disclosed
JP-H00925205-A 0001-01-01 JP disclosed