Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 11/20 | 0.56 |
| ▸ | CES1 | P23141 | 10/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL279769 | 1.00 | CES2 (0.56) | CES2CES1CYP2C19GAATSHR | |
| SCHEMBL204419 | 0.80 | CPT1B (0.52) | CES2CES1MAPTCYP3A4BLM | |
| SCHEMBL204420 | 0.80 | CPT1B (0.52) | CES2CES1MAPTCYP3A4BLM | |
| SCHEMBL13943817 | 0.80 | CES2 (0.62) | CES2CES1TSHRMAPTCYP3A4 | |
| SCHEMBL2755934 | 0.80 | CES2 (0.54) | CES2CES1CYP2C19TSHRMAPT | |
| SCHEMBL11797263 | 0.78 | CES2 (0.60) | CES2CES1MAPTL3MBTL1MAPK1 | |
| SCHEMBL11806648 | 0.78 | CES2 (0.60) | CES2CES1GAAMAPTTDP1 | |
| SCHEMBL11797258 | 0.78 | CES2 (0.60) | CES2CES1MAPTL3MBTL1MAPK1 | |
| SCHEMBL11806639 | 0.78 | CES2 (0.60) | CES2CES1GAAMAPTTDP1 | |
| Benzil SCHEMBL35210470 | 0.78 | CES2 (0.82) | CES2CES1CYP2C19TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564212-A2 | Process for the preparation of arylethylamines and substituted arylethylamines | HOECHST CELANESE CORPORATION (US) | 1993-10-06 | — | — | EP | claimed |
| EP-0564213-A2 | Process for the preparation of arylethylamines and substituted arylethylamines | HOECHST CELANESE CORPORATION (US) | 1993-10-06 | — | — | EP | claimed |
| US-5220066-A | Process for the preparation of arylethylamines and substituted arylethylamines | HOECHST CELANESE CORPORATION (US) | 1993-06-15 | — | — | US | claimed |
| US-5220067-A | Process for the preparation of arylethylamines and substituted arylethylamines | HOECHST CELANESE CORPORATION (US) | 1993-06-15 | — | — | US | claimed |
| EP-3186226-B1 | OXIME SULFONATE DERIVATIVES | BASF SE (DE) | 2020-06-17 | — | — | EP | disclosed |
| US-20190171099-A1 | POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT | BASF SE (DE) | 2019-06-06 | — | — | US | disclosed |
| US-10241399-B2 | Polymerizable composition comprising an oxime sulfonate as thermal curing agent | BASF SE (DE) | 2019-03-26 | — | — | US | disclosed |
| US-20170260132-A1 | OXIME SULFONATE DERIVATIVES | BASF SE (DE) | 2017-09-14 | — | — | US | disclosed |
| US-9310677-B2 | Polymerizable composition comprising an oxime sulfonate as thermal curing agent | BASF (DE) | 2016-04-12 | — | — | US | disclosed |
| US-20160060214-A1 | POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT | BASF SE (DE) | 2016-03-03 | — | — | US | disclosed |
| EP-2586307-B1 | Synergistic microbicidal compositions containing 1,2-benzisothiazolin-3-one (BIT) and capric acid | ROHM & HAAS (US) | 2014-06-25 | — | — | EP | disclosed |
| US-20130308219-A1 | POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT | BASF SE (DE) | 2013-11-21 | — | — | US | disclosed |
| US-5220066-A | Process for the preparation of arylethylamines and substituted arylethylamines | HOECHST CELANESE CORPORATION (US) | 1993-06-15 | — | — | US | disclosed |
| US-5220067-A | Process for the preparation of arylethylamines and substituted arylethylamines | HOECHST CELANESE CORPORATION (US) | 1993-06-15 | — | — | US | disclosed |
| US-5220067-A | Process for the preparation of arylethylamines and substituted arylethylamines | HOECHST CELANESE CORPORATION (US) | 1993-06-15 | — | — | US | disclosed |
| US-5220021-A | Geminal bisphosphonic acids and derivatives as anti-arthritic agents | THE UPJOHN COMPANY (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0466730-A1 | GEMINAL BISPHOSPHONIC ACIDS AND DERIVATIVES AS ANTI-ARTHRITIC AGENTS. | UPJOHN CO (US) | 1992-01-22 | — | — | EP | disclosed |
| WO-1990012017-A1 | GEMINAL BISPHOSPHONIC ACIDS AND DERIVATIVES AS ANTI-ARTHRITIC AGENTS | THE UPJOHN COMPANY (US) | 1990-10-18 | — | — | WO | disclosed |
| US-4172079-A | Preparation of 4-nitroisoxazoles | TEXACO INC. (US) | 1979-10-23 | — | — | US | disclosed |
| US-3986974-A | AROYL-N-HYDROXYFORMIMIDOYL HALIDES AS BLEACH ACTIVATORS | AMERICAN CYANAMID COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10241399-B2 | Polymerizable composition comprising an oxime sulfonate as thermal curing agent | SULT1E1, COX6B1, SULT1A1 | CES2 354/4885CES1 304/4885CYP2C19 189/4885 |
| US-20170260132-A1 | OXIME SULFONATE DERIVATIVES | CBR3, CBR1, C1R | CES2 254/4885CES1 267/4885CYP2C19 154/4885 |
| US-20190171099-A1 | POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT | SULT1E1, COX6B1, SULT1A1 | CES2 354/4885CES1 304/4885CYP2C19 189/4885 |
| US-20160060214-A1 | POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT | SULT1E1, COX6B1, SULT1A1 | CES2 354/4885CES1 304/4885CYP2C19 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.