Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149720 | 0.85 | ESR1 (0.38) | ADRB2ESR1PDCD1ESR2CD274 | |
| SCHEMBL5075045 | 0.78 | TSHR (0.67) | TSHRADRB2ESR1ESR2MAPK1 | |
| SCHEMBL16425762 | 0.78 | ADRB2 (0.56) | TSHRADRB2MAPK1TDP1 | |
| SCHEMBL10039362 | 0.77 | TYR (0.46) | ADRB2MAPK1 | |
| SCHEMBL1462968 | 0.77 | TSHR (0.50) | TSHRADRB2MAPK1TDP1 | |
| SCHEMBL14501580 | 0.77 | TSHR (0.50) | TSHRMAPK1TDP1 | |
| SCHEMBL14501581 | 0.77 | TSHR (0.50) | TSHRMAPK1TDP1 | |
| SCHEMBL1538493 | 0.75 | TSHR (0.30) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL21840890 | 0.74 | IDO1 (0.44) | TSHR | |
| SCHEMBL14417193 | 0.74 | ACHE (0.47) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960488-B2 | Aluminoxane compositions, their preparation, and their use in catalysis | ALBEMARLE CORPORATION (US) | 2011-06-14 | — | — | US | disclosed |
| US-20090088541-A1 | ALUMINOXANE COMPOSITIONS, THEIR PREPARATION, AND THEIR USE IN CATALYSIS | ALBEMARLE CORPORATION (US) | 2009-04-02 | — | — | US | disclosed |