SCHEMBL2044288

SCHEMBL2044288

C=CCC1(CC=C)C(=O)N(c2ccccc2)C(=O)N(c2ccccc2)C1=O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 9/20 0.56
PGR P06401 2/20 0.51
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
THPO P40225 1/20 0.39
GRK5 P34947 1/20 0.39
TYRO3 Q06418 1/20 0.39
DYRK1B Q9Y463 1/20 0.39
MGLL Q99685 1/20 0.38
MAPK1 P28482 1/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2047367 0.90 ELANE (0.50) ELANEPGRALDH1A1CYP1A2CYP3A4
SCHEMBL2047369 0.90 ELANE (0.50) ELANEPGRALDH1A1CYP1A2CYP3A4
SCHEMBL9184675 0.89 ELANE (0.53) ELANEPGRALDH1A1CYP1A2CYP3A4
SCHEMBL2043898 0.82 KDM4E (0.47) ELANEPGRALDH1A1CYP2C19GAA
SCHEMBL2047107 0.82 PGR (0.48) ELANEPGRALDH1A1CYP1A2CYP3A4
SCHEMBL17716273 0.78 ELANE (0.89) ELANEPGR
SCHEMBL4428745 0.77 ELANE (0.74) ELANEALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL2050106 0.74 ELANE (0.43) ELANEPGRALDH1A1GRK5TYRO3
SCHEMBL2050104 0.74 ELANE (0.43) ELANEPGRALDH1A1GRK5TYRO3
SCHEMBL10583889 0.74 PGR (0.39) ELANEPGRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964691-B2 5,5-diallyl-2,2-dimethyl-1,3-dioxane as monomer units; polymerization catalysts; heat resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-21 US disclosed
WO-2009038031-A1 BLOCK COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
US-20080214754-A1 DIENE POLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed
US-20080214755-A1 OLEFIN-DIENE COPOLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed