Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894517 | 0.92 | ELANE (0.45) | ELANEMAPTMAPK1POLBNPSR1 | |
| SCHEMBL11578594 | 0.88 | LMNA (0.45) | MAPTMAPK1L3MBTL1SRCALDH1A1 | |
| SCHEMBL9377254 | 0.87 | SRC (0.48) | ELANEL3MBTL1SRCPOLBCYP19A1 | |
| SCHEMBL29161884 | 0.81 | PRSS1 (0.46) | — | |
| SCHEMBL1450572 | 0.80 | LMNA (0.48) | L3MBTL1SRCALDH1A1POLBLMNA | |
| SCHEMBL649963 | 0.79 | TSHR (0.52) | L3MBTL1SRCPOLBNPSR1 | |
| SCHEMBL15438740 | 0.77 | KMT2A (0.42) | ELANEMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL15438216 | 0.77 | KMT2A (0.43) | ELANEMAPTALDH1A1LMNA | |
| SCHEMBL8303811 | 0.77 | MAPK1 (0.46) | MAPTMAPK1POLBNPSR1NR1I2 | |
| SCHEMBL2720079 | 0.76 | POLB (0.59) | L3MBTL1SRCPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010084507-A2 | PROCESS FOR THE PREPARATION OF N-METHYL-2-[3-(1-METHYL-4-PIPERIDYL)-1H-INDOL-5-YL]-ETHANESULFONAMIDE AND ITS ACID ADDITION SALTS | SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) | 2010-07-29 | — | — | WO | claimed |
| US-8748543-B2 | Polylactic acid film | TEIJIN LIMITED (JP) | 2014-06-10 | — | — | US | disclosed |
| CN-102203110-A | Trehalose compound, method for producing same, and pharmaceutical product containing the compound | OTSUKA CHEMICAL CO LTD | 2011-09-28 | — | — | CN | disclosed |
| US-20110224342-A1 | POLYLACTIC ACID FILM | TEIJIN LIMITED (JP) | 2011-09-15 | — | — | US | disclosed |
| EP-2330148-A1 | POLYLACTIC ACID FILM | Teijin Limited (JP) | 2011-06-08 | — | — | EP | disclosed |