Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KLK8 | O60259 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | KLK2 | P20151 | 2/20 | 0.42 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2044409 | 0.87 | ELANE (0.42) | SRCCYP19A1L3MBTL1ELANEPOLB | |
| SCHEMBL2720079 | 0.84 | POLB (0.59) | SRCL3MBTL1TDP1BTN3A1POLB | |
| SCHEMBL4945259 | 0.82 | SRC (0.54) | SRCL3MBTL1TDP1KLK8PLAU | |
| SCHEMBL27593432 | 0.82 | SRC (0.50) | SRCCYP19A1L3MBTL1TDP1ELANE | |
| SCHEMBL4082433 | 0.81 | CYP19A1 (0.47) | SRCCYP19A1L3MBTL1TDP1ELANE | |
| SCHEMBL1450572 | 0.81 | LMNA (0.48) | SRCL3MBTL1BTN3A1POLBMEN1 | |
| SCHEMBL10894517 | 0.81 | ELANE (0.45) | CYP19A1ELANEPOLBMEN1KMT2A | |
| SCHEMBL25135085 | 0.80 | ALDH1A1 (0.54) | SRCL3MBTL1TDP1PLAUELANE | |
| SCHEMBL1905315 | 0.80 | ALDH1A1 (0.44) | SRCL3MBTL1TDP1KLK8PLAU | |
| SCHEMBL27748585 | 0.80 | SRC (0.43) | SRCL3MBTL1TDP1KLK8PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192170-A1 | PROCESS FOR PREPARING ((1S,2S)-2-(5-METHYLPYRIDIN-2-YL)CYCLOPROPYL)METHANOL | MERCK SHARP & DOHME LLC (US) | 2023-10-05 | — | — | WO | claimed |
| EP-0380392-B1 | Derivatives of benzocycloalkenyl dihydroxyalkanoic acids, methods of making them and phrmaceuticals containing them | LIPHA (FR) | 1994-04-20 | — | — | EP | claimed |
| EP-0380392-A2 | Derivatives of benzocycloalkenyl dihydroxyalkanoic acids, methods of making them and phrmaceuticals containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-08-01 | — | — | EP | claimed |
| WO-2023192170-A1 | PROCESS FOR PREPARING ((1S,2S)-2-(5-METHYLPYRIDIN-2-YL)CYCLOPROPYL)METHANOL | MERCK SHARP & DOHME LLC (US) | 2023-10-05 | — | — | WO | disclosed |