Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900161 | 0.83 | MGLL (0.47) | MAPTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL29988767 | 0.83 | MGLL (0.47) | MAPTKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL20444565 | 0.81 | PDE6D (0.33) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL20444549 | 0.81 | PDE6D (0.35) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL17954513 | 0.77 | MAPT (0.37) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL17954479 | 0.77 | MAPT (0.37) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL20424965 | 0.77 | KMT2A (0.42) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL20424618 | 0.77 | KDM4E (0.42) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL22628196 | 0.77 | PGR (0.38) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL29843848 | 0.77 | KMT2A (0.42) | MAPTKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573985-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-01-18 | — | — | EP | disclosed |
| WO-2018138306-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-08-02 | — | — | WO | disclosed |