Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29843803 | 1.00 | KDM4E (0.42) | KDM4EMAPK1ATMP2RX4MAPT | |
| SCHEMBL29829444 | 0.81 | MGLL (0.50) | P2RX4MGLLMEN1KMT2AAHR | |
| SCHEMBL16604412 | 0.81 | MGLL (0.50) | P2RX4MGLLMEN1KMT2AAHR | |
| SCHEMBL29843848 | 0.79 | KMT2A (0.42) | KDM4EMAPK1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL20424965 | 0.79 | KMT2A (0.42) | KDM4EMAPK1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL20444647 | 0.77 | ALDH1A1 (0.43) | KDM4EMAPK1ATMMAPTSMN1; SMN2 | |
| SCHEMBL20444739 | 0.77 | MAPT (0.40) | KDM4EMAPK1MAPTNPSR1HPGD | |
| SCHEMBL26327435 | 0.77 | MGLL (0.41) | P2RX4MAPTSMN1; SMN2NPSR1MGLL | |
| SCHEMBL20444741 | 0.76 | MAOA (0.41) | HPGDTYMSMGLL | |
| SCHEMBL24893448 | 0.76 | AHR (0.42) | P2RX4MAPTSMN1; SMN2NPSR1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573985-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-01-18 | — | — | EP | disclosed |
| WO-2018138306-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-08-02 | — | — | WO | disclosed |
| WO-2018138306-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-08-02 | — | — | WO | disclosed |