Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398545 | 0.89 | MAPT (0.58) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL542358 | 0.87 | MAPT (0.53) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| Water SCHEMBL9474377 | 0.85 | MAPT (0.52) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL5026886 | 0.78 | PRKCA (0.60) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL13901278 | 0.78 | MAPT (0.61) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL1686207 | 0.76 | MAPT (0.36) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL9190664 | 0.76 | GABRP (0.43) | FAAHCNR1CNR2EGLN1KDM6B | |
| SCHEMBL23694892 | 0.76 | PHF8 (0.46) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL23693964 | 0.76 | PHF8 (0.46) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL23694900 | 0.76 | PHF8 (0.46) | MAPTMAPK1PRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964696-B2 | Chain extenders | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-06-21 | — | — | US | claimed |
| US-20090175921-A1 | Chain Extenders | POLYNOVO BIOMATERIALS PTY LIMITED | 2009-07-09 | — | — | US | claimed |
| EP-1945690-A1 | CHAIN EXTENDERS | Polynovo Biomaterials Pty Limited (AU) | 2008-07-23 | — | — | EP | claimed |
| WO-2007033418-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2007-03-29 | — | — | WO | claimed |
| US-20150105530-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LTD (AU) | 2015-04-16 | — | — | US | disclosed |
| EP-2195361-A1 | HIGH MODULUS POLYURETHANE AND POLYURETHANE/UREA COMPOSITIONS | Polynovo Biomaterials Limited (AU) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009043099-A1 | HIGH MODULUS POLYURETHANE AND POLYURETHANE/UREA COMPOSITIONS | POLYNOVO BIOMATERIALS LIMITED (AU) | 2009-04-09 | — | — | WO | disclosed |
| EP-1945690-A1 | CHAIN EXTENDERS | Polynovo Biomaterials Pty Limited (AU) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007033418-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090175921-A1 | Chain Extenders | UMPS, PUF60, SMC1A | MAPT 956/4885MAPK1 1706/4885PRKCA 2540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.