Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326018 | 0.88 | PDE3B (0.31) | PDE3BPDE3A | |
| SCHEMBL7325661 | 0.87 | FKBP5 (0.44) | PDE3BPDE3A | |
| SCHEMBL8756227 | 0.87 | PDE3B (0.30) | PDE3BPDE3A | |
| SCHEMBL384843 | 0.73 | CA12 (0.34) | PDE3BPDE3ANPC1TDP2NSD2 | |
| SCHEMBL29022516 | 0.71 | — | — | |
| SCHEMBL29550002 | 0.69 | AHR (0.48) | PDE3BPDE3AABL1PLCG1MEN1 | |
| SCHEMBL659375 | 0.69 | AHR (0.48) | PDE3BPDE3AABL1PLCG1MEN1 | |
| SCHEMBL6937 | 0.68 | MAOA (0.48) | NPC1TDP2CES1GAA | |
| SCHEMBL29408741 | 0.68 | MAOA (0.48) | NPC1TDP2CES1GAA | |
| SCHEMBL31712933 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250082652-A1 | SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2025-03-13 | — | — | US | claimed |
| EP-4460301-A1 | SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES | Universität zu Köln (DE) | 2024-11-13 | — | — | EP | claimed |
| EP-3720493-B1 | COMBINATIONS OF RIPK1- AND IKK-INHIBITORS FOR THE PREVENTION OR TREATMENT OF IMMUNE DISEASES | UNIV KOELN (DE) | 2024-07-24 | — | — | EP | claimed |
| CN-114457159-B | Method for detecting tumor cells or tumor cell fragments | 珠海圣美生物诊断技术有限公司 | 2023-09-19 | — | — | CN | claimed |
| WO-2023131576-A1 | SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2023-07-13 | — | — | WO | claimed |
| EP-4209213-A1 | SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES | Universität zu Köln (DE) | 2023-07-12 | — | — | EP | claimed |
| CN-114085911-B | Method for detecting tumor cells or tumor cell fragments | 珠海圣美生物诊断技术有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-114457159-A | Method for detecting tumor cells or tumor cell fragments | 珠海圣美生物诊断技术有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114085911-A | Method for detecting tumor cells or tumor cell fragments | 珠海圣美生物诊断技术有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-101842095-A | Formulations, methods and targets for tumor therapy | MING YU | 2010-09-22 | — | — | CN | claimed |
| EP-2178531-A2 | METHODS, COMPOSITION, TARGETS FOR COMBINATIONAL CANCER TREATMENTS | Yu, Ming (US) | 2010-04-28 | — | — | EP | claimed |
| WO-2009006555-A2 | METHODS, COMPOSITION, TARGETS FOR COMBINATIONAL CANCER TREATMENTS | YU, MING (US) | 2009-01-08 | — | — | WO | claimed |
| EP-1888060-A2 | NK-B INHIBITORS FOR THE TREATMENT OF MUSCULAR DYSTROPHY | A. T. Still University of Health Sciences (US) | 2008-02-20 | — | — | EP | claimed |
| US-20060280812-A1 | Compositions and methods for the treatment of muscular dystrophy | A.T. STILL UNIVERSITY OF HEATH SCIENCES | 2006-12-14 | — | — | US | claimed |
| WO-2006127930-A2 | NK-B INHIBITORS FOR THE TREATMENT OF MUSCULAR DYSTROPHY | A. T. STILL UNIVERSITY OF HEALTH SCIENCES (US) | 2006-11-30 | — | — | WO | claimed |
| EP-4705765-A2 | BUCCAL CELL DIAGNOSIS OF RISK IN FAMILIAL ARRHYTHMIA SYNDROMES | Beth Israel Deaconess Medical Center, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| US-20250082652-A1 | SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2025-03-13 | — | — | US | disclosed |
| WO-1988008706-A1 | PYRIDOOXAZINONE-PYRIDAZINONE AND PYRAZOLONE COMPOUNDS, CARDIOTONIC COMPOSITIONS INCLUDING THE SAME, AND THEIR USE | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1988-11-17 | — | — | WO | disclosed |
| WO-1988008705-A1 | PYRIDOOXAZINONE-PYRIDONE COMPOUNDS, CARDIOTONIC COMPOSITIONS INCLUDING THE SAME, AND THEIR USES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1988-11-17 | — | — | WO | disclosed |
| WO-1988008705-A1 | PYRIDOOXAZINONE-PYRIDONE COMPOUNDS, CARDIOTONIC COMPOSITIONS INCLUDING THE SAME, AND THEIR USES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1988-11-17 | — | — | WO | disclosed |