Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL28620201 | 0.84 | ALDH1A1 (0.37) | NPC1 | |
| SCHEMBL24631376 | 0.77 | PTPRC (0.37) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL29588358 | 0.74 | MAOA (0.59) | GAANPC1MAOAMAOB | |
| SCHEMBL813060 | 0.74 | MAOA (0.59) | GAANPC1MAOAMAOB | |
| SCHEMBL7850857 | 0.73 | MAPK14 (0.34) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL2044670 | 0.73 | PDE3B (0.36) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL15763902 | 0.71 | MAOA (0.46) | CA12CA9TDP1HPGDMAOA | |
| Acetic Acid SCHEMBL5593975 | 0.70 | MAOA (0.47) | GAAMAOAMAOB | |
| Quinoline SCHEMBL27357350 | 0.70 | ALDH1A1 (0.52) | MEN1KMT2ANPC1MAOAMAOB | |
| SCHEMBL13028725 | 0.69 | CA12 (0.36) | CA12CA9TDP2NSD2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116135858-B | Furanopyridone compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2025-04-01 | — | — | CN | claimed |
| US-20250066360-A1 | PYRIDINE-CONTAINING POLYCYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2025-02-27 | — | — | US | claimed |
| EP-4464694-A1 | PYRIDINE-CONTAINING POLYCYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2024-11-20 | — | — | EP | claimed |
| CN-118525005-A | Polycyclic derivative containing pyridine, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-20 | — | — | CN | claimed |
| WO-2023134764-A1 | PYRIDINE-CONTAINING POLYCYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-20 | — | — | WO | claimed |
| CN-116444493-A | Derivative containing double parallel rings, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-07-18 | — | — | CN | claimed |
| WO-2023088493-A1 | FURO-PYRIDONE COMPOUND AND USE THEREOF | 中国科学院广州生物医药与健康研究院 | 2023-05-25 | — | — | WO | claimed |
| CN-116135858-A | Furanopyridone compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-05-19 | — | — | CN | claimed |
| CN-115943959-A | Fluorine-containing pyridofuranone soluble liquid and preparation method thereof | 上海生农生化制品股份有限公司 | 2023-04-11 | — | — | CN | claimed |
| EP-3644992-B1 | 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME LLC (US) | 2023-03-29 | — | — | EP | claimed |
| WO-2019000238-A1 | 5-(PYRIDIN-3-YL)OXAZOLE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME CORP. (US) | 2019-01-03 | — | — | WO | claimed |
| WO-2019005589-A1 | 5-(PYRIDIN-3-YL)OXAZOLE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME CORP. (US) | 2019-01-03 | — | — | WO | claimed |
| WO-2019005587-A1 | 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME CORP. (US) | 2019-01-03 | — | — | WO | claimed |
| WO-2019000236-A1 | 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME CORP. (US) | 2019-01-03 | — | — | WO | claimed |
| EP-1791845-A2 | FURANOPYRIDINE DERIVATIVES AS ACK1 AND LCK MODULATORS | AMGEN INC. (US) | 2007-06-06 | — | — | EP | claimed |
| WO-2006130160-A2 | FURANOPYRIDINE DERIVATIVES AS ACK1 AND LCK MODULATORS | AMGEN INC. (US) | 2006-12-07 | — | — | WO | claimed |
| US-20060046977-A1 | Furanopyridine derivatives and methods of use | AMGEN INC. | 2006-03-02 | — | — | US | claimed |
| US-4363664-A | AQEOUS DISPERSION CONTAINING DYESTUFF PRECURSORS AND SURFACTANT | STERLING DRUG INC. (US) | 1982-12-14 | — | — | US | claimed |
| EP-0006772-B1 | THIENO AND FUROPYRIDONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINAL PREPARATIONS CONTAINING THEM | OMNIUM FINANCIER AQUITAINE POUR L'HYGIENE ET LA SANTE - SANOFI (FR) | 1981-11-04 | — | — | EP | claimed |
| EP-0006772-A1 | Thieno and furopyridone derivatives, process for their preparation and medicinal preparations containing them | OMNIUM FINANCIER AQUITAINE POUR L'HYGIENE ET LA SANTE - SANOFI (FR) | 1980-01-09 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060046977-A1 | Furanopyridine derivatives and methods of use | LCK, NFATC1, MINK1 | CA12 3850/4885CA9 2221/4885TDP2 1338/4885 |
| US-20250066360-A1 | PYRIDINE-CONTAINING POLYCYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | MYD88, NOD1, LITAF | CA12 4459/4885CA9 4592/4885TDP2 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.