Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | BCKDK | O14874 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20563255 | 0.81 | USP30 (0.33) | USP30P4HBLIPGLPLF2 | |
| SCHEMBL20564062 | 0.79 | PTPN1 (0.34) | ALDH1A1HPGDTSHRUSP30P4HB | |
| SCHEMBL20505332 | 0.78 | F2 (0.36) | DAOALDH1A1HPGDUSP30P4HB | |
| SCHEMBL20505195 | 0.76 | TSHR (0.36) | ALDH1A1HPGDTSHRUSP30 | |
| SCHEMBL824177 | 0.75 | JAK2 (0.32) | LIPGLPL | |
| SCHEMBL20505486 | 0.72 | RXRA (0.38) | ALDH1A1USP30MAPK1F2F11 | |
| SCHEMBL17239587 | 0.71 | TSHR (0.35) | ALDH1A1TSHR | |
| SCHEMBL28554864 | 0.71 | ALDH1A1 (0.36) | ALDH1A1HPGDTSHRUSP30MAPK1 | |
| SCHEMBL20505078 | 0.70 | CYP3A4 (0.36) | ALDH1A1HPGDTSHRUSP30 | |
| SCHEMBL28519289 | 0.69 | DAO (0.36) | DAOLIPGMAPK1LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356352-B1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-19 | — | — | EP | disclosed |
| EP-3356352-B1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-19 | — | — | EP | disclosed |
| US-10548317-B2 | Pesticidally active pyrazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-04 | — | — | US | disclosed |
| US-10548317-B2 | Pesticidally active pyrazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-04 | — | — | US | disclosed |
| US-20180263242-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-20 | — | — | US | disclosed |
| EP-3356352-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2018-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180263242-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | ACHE, AADAC, API5 | DAO 2725/4885ALDH1A1 265/4885HPGD 1107/4885 |
| US-10548317-B2 | Pesticidally active pyrazole derivatives | ACHE, AADAC, API5 | DAO 2725/4885ALDH1A1 265/4885HPGD 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.