Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 3/20 | 0.45 |
| ▸ | CD74 | P04233 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20448919 | 0.86 | CYP1B1 (0.51) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL20546959 | 0.85 | SMN1; SMN2 (0.50) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16296890 | 0.80 | TSHR (0.80) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28452863 | 0.73 | MGAM (0.51) | TSHRLMNAALDH1A1GAAMAPK1 | |
| SCHEMBL17312313 | 0.68 | TSHR (0.65) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2757835 | 0.65 | MIF (0.71) | TSHRHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28537271 | 0.65 | TSHR (0.66) | TSHRLMNAALDH1A1GAAMAPK1 | |
| SCHEMBL68178 | 0.64 | CALM1 (0.79) | TSHRLMNAALDH1A1GAAMAPK1 | |
| SCHEMBL17780116 | 0.64 | PTPN1 (0.82) | TSHRLMNAALDH1A1GAAMAPK1 | |
| SCHEMBL29604390 | 0.64 | PTPN1 (0.82) | TSHRLMNAALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3355719-A1 | USE OF CERTAIN HYDROXYBENZOIC ACID AMIDES FOR MASKING UNPLEASANT TASTE IMPRESSIONS | Symrise AG (DE) | 2018-08-08 | — | — | EP | disclosed |