Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169821 | 0.79 | BACE1 (0.54) | BACE1L3MBTL1ALDH1A1MEN1USP2 | |
| SCHEMBL3220531 | 0.74 | ALDH1A1 (0.70) | BACE1L3MBTL1ALDH1A1MEN1USP2 | |
| SCHEMBL16978734 | 0.72 | BACE1 (0.59) | BACE1L3MBTL1ALDH1A1MEN1USP2 | |
| SCHEMBL15567273 | 0.72 | BACE1 (0.59) | BACE1L3MBTL1ALDH1A1MEN1USP2 | |
| SCHEMBL16967148 | 0.72 | BACE1 (0.59) | BACE1L3MBTL1ALDH1A1MEN1USP2 | |
| SCHEMBL15209922 | 0.72 | ADRA2C (0.56) | ALDH1A1LMNAADRA2AADRA2BADRA2C | |
| SCHEMBL28385360 | 0.69 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1MEN1MAPTHTT | |
| SCHEMBL20819316 | 0.68 | ALDH1A1 (0.40) | ALDH1A1ADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL3211895 | 0.68 | BACE1 (0.83) | BACE1L3MBTL1ALDH1A1MEN1USP2 | |
| SCHEMBL3211906 | 0.68 | BACE1 (0.83) | BACE1L3MBTL1ALDH1A1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448404-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | APEIRON SYNTHESIS S.A. (PL) | 2025-10-21 | — | — | US | disclosed |
| EP-3356379-B2 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | APEIRON SYNTHESIS SA (PL) | 2025-09-03 | — | — | EP | disclosed |
| US-20250066402-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | APEIRON SYNTHESIS SA (PL) | 2025-02-27 | — | — | US | disclosed |
| US-12173015-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | APEIRON SYNTHESIS S.A. (PL) | 2024-12-24 | — | — | US | disclosed |
| US-11976085-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | Aperion Synthesis S.A. (PL) | 2024-05-07 | — | — | US | disclosed |
| US-20240076308-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | APEIRON SYNTHESIS SA (PL) | 2024-03-07 | — | — | US | disclosed |
| US-20220073549-A1 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | APEIRON SYNTHESIS SA (PL) | 2022-03-10 | — | — | US | disclosed |
| US-11192911-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | APEIRON SYNTHESIS S.A. (PL) | 2021-12-07 | — | — | US | disclosed |
| CN-108137631-B | Process for preparing ruthenium complexes and intermediates thereof and their use in olefin metathesis | 阿派朗合成公司 | 2021-04-16 | — | — | CN | disclosed |
| EP-3356379-B1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | APEIRON SYNTHESIS SA (PL) | 2021-03-10 | — | — | EP | disclosed |
| US-20180298046-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | APEIRON SYNTHESIS S.A. (PL) | 2018-10-18 | — | — | US | disclosed |
| EP-3356379-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | Apeiron Synthesis S.A. (PL) | 2018-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12448404-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | CYP2E1, CYP1A1, REV1 | BACE1 1421/4885L3MBTL1 3605/4885ALDH1A1 580/4885 |
| US-20220073549-A1 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | POR, CYP1B1, CYP4F11 | BACE1 918/4885L3MBTL1 3997/4885ALDH1A1 406/4885 |
| US-11976085-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | POR, CYP1B1, CYP4F11 | BACE1 918/4885L3MBTL1 3997/4885ALDH1A1 406/4885 |
| US-11192911-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | POR, CYP1B1, CYP4F11 | BACE1 918/4885L3MBTL1 3997/4885ALDH1A1 406/4885 |
| US-20180298046-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | POR, CYP1B1, CYP4F11 | BACE1 918/4885L3MBTL1 3997/4885ALDH1A1 406/4885 |
| US-12173015-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | POR, CYP1B1, CYP4F11 | BACE1 918/4885L3MBTL1 3997/4885ALDH1A1 406/4885 |
| US-20250066402-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | CYP2E1, CYP1A1, REV1 | BACE1 1421/4885L3MBTL1 3605/4885ALDH1A1 580/4885 |
| US-20240076308-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | POR, CYP1B1, CYP4F11 | BACE1 918/4885L3MBTL1 3997/4885ALDH1A1 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.