SCHEMBL2044938

SCHEMBL2044938

Cc1cc(C)c2c(c1)C(O)C(C)C2

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
UGT2B17 O75795 2/20 0.49
TAS1R3 Q7RTX0 2/20 0.32
TAS1R1 Q7RTX1 2/20 0.32
TAS1R2 Q8TE23 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15822109 0.81 UGT2B17 (0.35) UGT2B17
SCHEMBL1736434 0.77 UGT2B17 (0.41) UGT2B17
SCHEMBL1736688 0.77 UGT2B17 (0.41) UGT2B17
SCHEMBL1735322 0.77 UGT2B17 (0.41) UGT2B17
SCHEMBL1736571 0.77 UGT2B17 (0.41) UGT2B17
SCHEMBL2929777 0.77 UGT2B17 (0.41) UGT2B17
SCHEMBL1734430 0.77 UGT2B17 (0.41) UGT2B17
SCHEMBL30666708 0.73 ACHE (0.41)
SCHEMBL7622974 0.73 ACHE (0.41)
SCHEMBL3664467 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178636-B2 Process for the preparation of atactic 1-butene polymers BASELL POLYOLEFINE GMBH (DE) 2012-05-15 US disclosed
US-7964679-B2 1-Butene polymer polymerization catalyst system: a Hf, Ti or Zr metallocene having an indene ring and a fluorene ring bridged by a silane group; an alumoxane or a compound that forms an alkyl metallocene cation; and an organoaluminum compound; (2,4,6-trimethylindenyl)(9-fluorenyl)dimethylsilane BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2011-06-21 US disclosed
EP-1753792-B1 PROCESS FOR THE PREPARATION OF ATACTIC 1-BUTENE POLYMERS BASELL POLYOLEFINE GMBH (DE) 2009-10-14 EP disclosed
US-20090005523-A1 Process for the Preparation of Atactic 1-Butene Polymers BASELL POLYEFINE GMBH (DE) 2009-01-01 US disclosed
US-20080269439-A1 Process for the Polymerization of Alpha Olefins BASELL POLYOLEFINE GMBH (DE) 2008-10-30 US disclosed
EP-1877453-A1 PROCESS FOR THE POLYMERIZATION OF ALPHA OLEFINS Basell Polyolefine GmbH (DE) 2008-01-16 EP disclosed
EP-1753792-A1 PROCESS FOR THE PREPARATION OF ATACTIC 1-BUTENE POLYMERS Basell Polyolefine GmbH (DE) 2007-02-21 EP disclosed
WO-2006117285-A1 PROCESS FOR THE POLYMERIZATION OF ALPHA OLEFINS BASELL POLYOLEFINE GMBH (DE) 2006-11-09 WO disclosed
WO-2005105865-A1 PROCESS FOR THE PREPARATION OF ATACTIC 1-BUTENE POLYMERS BASELL POLYOLEFINE GMBH (DE) 2005-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269439-A1 Process for the Polymerization of Alpha Olefins PYM1, CCNT1, HAO2 UGT2B17 1060/4885TAS1R3 2618/4885TAS1R1 1524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.