Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 3/20 | 0.61 |
| ▸ | CLK2 | P49760 | 17/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 15/20 | 0.61 |
| ▸ | CLK3 | P49761 | 13/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20453136 | 0.96 | CLK2 (0.68) | WNT1CLK2DYRK1ACLK3 | |
| SCHEMBL20452935 | 0.96 | CLK2 (0.66) | WNT1CLK2DYRK1ACLK3 | |
| SCHEMBL18476427 | 0.95 | CLK2 (0.65) | WNT1CLK2DYRK1ACLK3 | |
| SCHEMBL20453282 | 0.95 | CLK2 (0.58) | WNT1CLK2DYRK1ACLK3 | |
| SCHEMBL20453026 | 0.94 | CLK2 (0.58) | WNT1CLK2DYRK1ACLK3 | |
| SCHEMBL20452894 | 0.94 | CLK2 (0.58) | WNT1CLK2DYRK1ACLK3 | |
| SCHEMBL20452921 | 0.94 | CLK2 (0.58) | WNT1CLK2DYRK1ACLK3 | |
| SCHEMBL20464945 | 0.94 | CLK2 (0.59) | WNT1CLK2DYRK1ACLK3 | |
| SCHEMBL20452917 | 0.94 | CLK2 (0.62) | WNT1CLK2DYRK1ACLK3 | |
| SCHEMBL18439370 | 0.94 | CLK2 (0.60) | WNT1CLK2DYRK1ACLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10188634-B2 | 3-(3H-imidazo[4,5-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof | SAMUMED, LLC (US) | 2019-01-29 | — | — | US | claimed |
| US-20180221354-A1 | 3-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-PYRAZOLO[4,3-B]PYRIDINES AND THERAPEUTIC USES THEREOF | VICKERS VENTURE FUND VI (PLAN) PTE. LTD. (SG) | 2018-08-09 | — | — | US | claimed |
| US-10188634-B2 | 3-(3H-imidazo[4,5-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof | SAMUMED, LLC (US) | 2019-01-29 | — | — | US | disclosed |
| US-20180221354-A1 | 3-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-PYRAZOLO[4,3-B]PYRIDINES AND THERAPEUTIC USES THEREOF | VICKERS VENTURE FUND VI (PLAN) PTE. LTD. (SG) | 2018-08-09 | — | — | US | disclosed |
| US-20180221354-A1 | 3-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-PYRAZOLO[4,3-B]PYRIDINES AND THERAPEUTIC USES THEREOF | VICKERS VENTURE FUND VI (PLAN) PTE. LTD. (SG) | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180221354-A1 | 3-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-PYRAZOLO[4,3-B]PYRIDINES AND THERAPEUTIC USES THEREOF | WNT3, WNT3A, WNT1 | WNT1 3/4885CLK2 2323/4885DYRK1A 1023/4885 |
| US-10188634-B2 | 3-(3H-imidazo[4,5-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof | WNT1, WNT3, WNT3A | WNT1 1/4885CLK2 2569/4885DYRK1A 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.