Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459474 | 0.81 | SMN1; SMN2 (0.49) | CYP2A6SMN1; SMN2ALDH1A1KDM4ERAB9A | |
| SCHEMBL1613623 | 0.77 | S1PR3 (0.47) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL1613624 | 0.77 | S1PR3 (0.47) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL6759842 | 0.77 | CYP2A6 (0.47) | CYP2A6CHRNA7SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29449994 | 0.77 | MAOA (0.49) | CYP2A6SMN1; SMN2ALDH1A1KDM4EGRK6 | |
| SCHEMBL940731 | 0.77 | MAOA (0.49) | CYP2A6SMN1; SMN2ALDH1A1KDM4EGRK6 | |
| SCHEMBL11926858 | 0.77 | CYP2A6 (0.62) | CYP2A6CHRNA7SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1612258 | 0.74 | CYP1A2 (0.40) | ALDH1A1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL1612257 | 0.74 | CYP1A2 (0.40) | ALDH1A1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL1187043 | 0.73 | CYP2A6 (0.53) | CYP2A6CHRNA7SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120291159-A1 | Azoline Compounds for Combating Invertebrate Pests | BASF SE (DE) | 2012-11-15 | — | — | US | disclosed |
| WO-2011073444-A2 | AZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2011-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120291159-A1 | Azoline Compounds for Combating Invertebrate Pests | CRY1, PIR, DDT | CYP2A6 1529/4885CHRNA7 1709/4885SMN1; SMN2 2645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.