Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1612257 | 1.00 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL1613624 | 0.83 | S1PR3 (0.47) | CYP1A2CYP2C9CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL1613623 | 0.83 | S1PR3 (0.47) | CYP1A2CYP2C9CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL1611874 | 0.80 | S1PR3 (0.39) | CYP1A2CYP2C9CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL1611876 | 0.80 | S1PR3 (0.39) | CYP1A2CYP2C9CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL4459474 | 0.76 | SMN1; SMN2 (0.49) | CYP1A2CYP2C9CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL1609796 | 0.75 | ALDH1A1 (0.41) | CYP1A2CYP2C9CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL1609795 | 0.75 | ALDH1A1 (0.41) | CYP1A2CYP2C9CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL2045441 | 0.74 | CYP2A6 (0.44) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL17295794 | 0.74 | CRHBP (0.47) | ALDH1A1KMT2AMEN1RAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069338-B1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2012-11-28 | — | — | EP | disclosed |
| EP-2332937-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| EP-2330106-A1 | Insecticidal isoxazolines | Bayer CropScience AG (DE) | 2011-06-08 | — | — | EP | disclosed |
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | US | disclosed |
| US-20100249191-A1 | N-Methyl benzamide derivatives | BAYER CROPSCIENCE SA (FR) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086886-A2 | INSECTICIDAL ISOXAZOLINES | HAX1, INA, CYCS | CYP1A2 88/4885CYP2C9 579/4885CYP2C19 1455/4885 |
| US-20100249191-A1 | N-Methyl benzamide derivatives | GNMT, SCN1A, INA | CYP1A2 219/4885CYP2C9 974/4885CYP2C19 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.