Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045474 | 1.00 | TSHR (0.44) | TSHRLMNAMAPK1HTTL3MBTL1 | |
| SCHEMBL6292705 | 0.91 | SMN1; SMN2 (0.50) | TSHRLMNAMAPK1HTTL3MBTL1 | |
| SCHEMBL3689392 | 0.87 | TSHR (0.48) | TSHRLMNAL3MBTL1TYMPGAA | |
| SCHEMBL3958996 | 0.87 | TSHR (0.48) | TSHRLMNAL3MBTL1TYMPGAA | |
| SCHEMBL8007984 | 0.87 | TSHR (0.48) | TSHRLMNAL3MBTL1TYMPGAA | |
| SCHEMBL3689389 | 0.85 | TSHR (0.47) | TSHRLMNAMAPK1L3MBTL1TYMP | |
| SCHEMBL7651351 | 0.85 | CES1 (0.48) | TSHRLMNAMAPK1HTTL3MBTL1 | |
| SCHEMBL7805644 | 0.85 | CES1 (0.48) | TSHRLMNAMAPK1HTTL3MBTL1 | |
| SCHEMBL3689388 | 0.85 | TSHR (0.47) | TSHRLMNAMAPK1L3MBTL1TYMP | |
| SCHEMBL9900446 | 0.85 | CES2 (0.50) | TSHRLMNAHTTTYMPGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338544-B2 | Polymers functionalized with polyoxime compounds and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2012-12-25 | — | — | US | claimed |
| EP-2516475-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | Bridgestone Corporation (JP) | 2012-10-31 | — | — | EP | claimed |
| US-20110152449-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | claimed |
| US-8338544-B2 | Polymers functionalized with polyoxime compounds and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2012-12-25 | — | — | US | disclosed |
| EP-2516475-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | Bridgestone Corporation (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20110152449-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |