Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | JAK3 | P52333 | 8/20 | 0.46 |
| ▸ | JAK2 | O60674 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832176 | 0.85 | TSHR (0.55) | GABRA1GABRB2GABRB1GABRA3JAK3 | |
| SCHEMBL2045109 | 0.80 | HSD17B10 (0.43) | MEN1ALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL9023551 | 0.78 | CA12 (0.54) | GABRA1GABRB2GABRB1GABRA3JAK3 | |
| SCHEMBL8911574 | 0.72 | CYP1A2 (0.49) | GABRA1GABRB2GABRB1GABRA3JAK3 | |
| SCHEMBL396948 | 0.72 | CLEC4M (0.56) | GABRA1GABRB2GABRB1GABRA3CA12 | |
| SCHEMBL7552732 | 0.71 | GABRA1 (0.52) | GABRA1GABRB2GABRB1GABRA3JAK3 | |
| SCHEMBL10930498 | 0.70 | NR4A2 (0.51) | GABRA1GABRB2MEN1ALDH1A1KMT2A | |
| SCHEMBL7823262 | 0.70 | TDP1 (0.47) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL2050904 | 0.70 | GABRA1 (0.61) | GABRA1GABRB2GABRB1GABRA3CA12 | |
| SCHEMBL2461799 | 0.70 | KDM4E (0.60) | MEN1ALDH1A1HPGDKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329689-B2 | Substituted indoles and a method for the production and use thereof | Ivachtchenko, Alexandre Vasilievich (US) | 2012-12-11 | — | — | US | disclosed |
| US-20110160197-A1 | Substituted Indoles and a Method for the Production and Use Thereof | ALLA CHEM, LLC | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160197-A1 | Substituted Indoles and a Method for the Production and Use Thereof | IDO1, HCCS, CHRM1 | GABRA1 2546/4885GABRB2 3131/4885GABRB1 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.