Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045552 | 0.80 | GABRA1 (0.47) | HSD17B10MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2461799 | 0.79 | KDM4E (0.60) | HSD17B10KDM4EGAAMEN1ALDH1A1 | |
| SCHEMBL6838151 | 0.78 | CYP1A2 (0.49) | HSD17B10CYP1A2F7F3KDM4E | |
| SCHEMBL4796014 | 0.75 | PRKAB2 (0.40) | F7F3KDM4EPRKAB2PRKAG1 | |
| SCHEMBL2003960 | 0.71 | GAA (0.58) | HSD17B10CYP1A2F7F3KDM4E | |
| SCHEMBL17429810 | 0.70 | CYP1A2 (0.41) | HSD17B10CYP1A2F7F3KDM4E | |
| Hydrochloric Acid SCHEMBL5008105 | 0.69 | KDM4E (0.48) | HSD17B10KDM4EGAAMEN1ALDH1A1 | |
| SCHEMBL16597465 | 0.67 | GPR84 (0.51) | HSD17B10CYP1A2F7F3KDM4E | |
| SCHEMBL6451616 | 0.67 | HSD17B10 (0.47) | HSD17B10CYP1A2F7F3KDM4E | |
| SCHEMBL28360290 | 0.65 | CYP1A2 (0.50) | HSD17B10CYP1A2KDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160197-A1 | Substituted Indoles and a Method for the Production and Use Thereof | ALLA CHEM, LLC | 2011-06-30 | — | — | US | claimed |
| EP-2036889-A2 | SUBSTITUTED INDOLES AND A METHOD FOR THE PRODUCTION AND USE THEREOF | Alla Chem, LLC. (US) | 2009-03-18 | — | — | EP | claimed |
| US-8329689-B2 | Substituted indoles and a method for the production and use thereof | Ivachtchenko, Alexandre Vasilievich (US) | 2012-12-11 | — | — | US | disclosed |
| US-20110160197-A1 | Substituted Indoles and a Method for the Production and Use Thereof | ALLA CHEM, LLC | 2011-06-30 | — | — | US | disclosed |
| EP-2036889-A2 | SUBSTITUTED INDOLES AND A METHOD FOR THE PRODUCTION AND USE THEREOF | Alla Chem, LLC. (US) | 2009-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160197-A1 | Substituted Indoles and a Method for the Production and Use Thereof | IDO1, HCCS, CHRM1 | HSD17B10 361/4885CYP1A2 34/4885F7 2767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.