Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832176 | 0.85 | TSHR (0.55) | NPSR1ALDH1A1TSHRMAPTHPGD | |
| SCHEMBL6317736 | 0.80 | NPSR1 (0.49) | TDP1NPSR1ALDH1A1TSHRMAPT | |
| SCHEMBL7835246 | 0.71 | TDP1 (0.52) | TDP1NPSR1ALDH1A1TSHRHPGD | |
| SCHEMBL7837012 | 0.70 | TSHR (0.47) | NPSR1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL7835009 | 0.70 | TSHR (0.47) | NPSR1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL2045552 | 0.70 | GABRA1 (0.47) | ALDH1A1HPGDKMT2AMEN1L3MBTL1 | |
| SCHEMBL3264030 | 0.70 | NR4A2 (0.61) | TDP1ALDH1A1TSHRLMNARAB9A | |
| SCHEMBL7822288 | 0.70 | RAB9A (0.47) | TDP1NPSR1ALDH1A1TSHRMAPT | |
| SCHEMBL7835107 | 0.70 | TSHR (0.46) | NPSR1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL7832141 | 0.70 | NPSR1 (0.48) | TDP1NPSR1ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144415-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000042045-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | disclosed |