SCHEMBL2045569

SCHEMBL2045569

O=CC(c1ccncn1)c1ccc(Cl)s1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
P2RX7 Q99572 1/20 0.31
GABBR2 O75899 1/20 0.31
GABBR1 Q9UBS5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2048460 0.78 CYP19A1 (0.35) ALDH1A1GABBR2GABBR1
SCHEMBL7825242 0.74 CYP19A1 (0.42) MEN1KMT2A
SCHEMBL28801425 0.73 GABBR2 (0.31) GABBR2GABBR1
SCHEMBL2041780 0.73 HRH4 (0.38)
SCHEMBL2042915 0.71 FFAR2 (0.33) GABBR2GABBR1
SCHEMBL2554967 0.68 HSP90AA1 (0.38) P2RX7
SCHEMBL27894259 0.66 LMNA (0.37) GABBR2GABBR1
SCHEMBL16402794 0.65 HSP90AA1 (0.35) ALDH1A1P2RX7
SCHEMBL15058024 0.65 HSP90AA1 (0.35) P2RX7
SCHEMBL28801423 0.65 GABBR2 (0.37) MEN1NPC1ALDH1A1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516423-A1 THIENYLPYRI (MI) DINYLAZOLE AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI Bayer CropScience AG (DE) 2012-10-31 EP disclosed
WO-2011076725-A1 THIENYLPYRI (MI) DINYLAZOLE AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI BAYER CROPSCIENCE AG (DE) 2011-06-30 WO disclosed