Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11799532 | 0.81 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1MAOA | |
| SCHEMBL18282707 | 0.80 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1MAOA | |
| SCHEMBL24394078 | 0.77 | OPRL1 (0.53) | OPRL1OPRM1OPRK1OPRD1MAOA | |
| SCHEMBL29588372 | 0.77 | SLC6A3 (0.53) | OPRL1OPRM1OPRK1OPRD1MAOA | |
| SCHEMBL18472678 | 0.77 | OPRL1 (0.52) | OPRL1OPRM1OPRK1OPRD1MAOA | |
| SCHEMBL20455679 | 0.76 | OPRL1 (0.44) | OPRL1OPRM1OPRK1OPRD1MAOA | |
| SCHEMBL653874 | 0.76 | DRD2 (0.59) | OPRL1OPRM1OPRK1OPRD1MAOA | |
| SCHEMBL20470478 | 0.76 | TACR1 (0.46) | OPRL1OPRM1OPRK1OPRD1SLC6A4 | |
| SCHEMBL20455678 | 0.75 | SLC6A3 (0.56) | OPRL1OPRM1OPRK1OPRD1MAOA | |
| Hydrochloric Acid SCHEMBL23578391 | 0.75 | DRD2 (0.58) | OPRL1OPRM1OPRK1OPRD1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325522-B | Liquid crystal compounds | 默克专利股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| WO-2018141759-A1 | LIQUID-CRYSTALLINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | WO | disclosed |
| WO-2018141759-A1 | LIQUID-CRYSTALLINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | WO | disclosed |