Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20455678 | 0.98 | SLC6A3 (0.56) | SLC6A3OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL24394078 | 0.96 | OPRL1 (0.53) | SLC6A3OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL18282707 | 0.91 | OPRL1 (0.55) | SLC6A3OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL24398040 | 0.90 | P2RY14 (0.49) | SLC6A3OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL3127047 | 0.82 | OPRL1 (0.49) | SLC6A3OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL24397813 | 0.82 | OPRL1 (0.49) | SLC6A3OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL653874 | 0.82 | DRD2 (0.59) | SLC6A3OPRL1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL23578391 | 0.81 | DRD2 (0.58) | SLC6A3OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL9034707 | 0.81 | OPRL1 (0.48) | SLC6A3OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL24397808 | 0.81 | OPRL1 (0.44) | SLC6A3OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237408-A1 | ITACONIC ACID DERIVATIVES | Sitryx Therapeutics Limited (GB) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022090723-A1 | ITACONIC ACID DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2022-05-05 | — | — | WO | disclosed |