Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12597876 | 0.83 | ALDH1A1 (0.38) | LMNAMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL26709435 | 0.81 | HSP90AA1 (0.38) | LMNAMAPTNR4A2L3MBTL1MEN1 | |
| SCHEMBL18310640 | 0.79 | NOS2 (0.34) | KDM4EPOLB | |
| SCHEMBL14066753 | 0.77 | KDM4E (0.35) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL23872365 | 0.74 | DHODH (0.33) | KDM4EPOLBHSP90AA1APOBEC3G | |
| SCHEMBL11985884 | 0.72 | LMNA (0.42) | LMNAMAPTNR4A2L3MBTL1MEN1 | |
| SCHEMBL28251597 | 0.72 | LMNA (0.42) | LMNAMAPTNR4A2L3MBTL1MEN1 | |
| SCHEMBL12733909 | 0.70 | SMN1; SMN2 (0.47) | L3MBTL1MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL20457088 | 0.70 | LMNA (0.37) | LMNAMAPTNR4A2L3MBTL1MEN1 | |
| SCHEMBL20457099 | 0.70 | KDM4E (0.34) | LMNAALDH1A1MAPK1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040804-B2 | Compounds targeting proteins, compositions, methods, and uses thereof | BIOTHERYX, INC. (US) | 2018-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10040804-B2 | Compounds targeting proteins, compositions, methods, and uses thereof | CKS1B, IKZF3, EPAS1 | LMNA 3372/4885MAPT 774/4885NR4A2 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.