Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860701 | 0.76 | ADH1B (0.36) | CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10311789 | 0.74 | ALOX5 (0.43) | TBXA2RCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7597476 | 0.74 | CYP1A2 (0.33) | TBXA2RCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7440315 | 0.74 | EPHX1 (0.39) | TBXA2RCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL27475440 | 0.74 | EPHX1 (0.39) | TBXA2RCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL20707964 | 0.72 | TBXA2R (0.31) | TBXA2R | |
| SCHEMBL29953593 | 0.71 | ADH1B (0.37) | TBXA2RCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8976389 | 0.71 | EPHX1 (0.35) | TBXA2RCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14653055 | 0.70 | SIGMAR1 (0.34) | CHRM2CHRM4CHRM5CHRM1EPHX1 | |
| SCHEMBL4254639 | 0.70 | SIGMAR1 (0.34) | CHRM2CHRM4CHRM5CHRM1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040819-B2 | Chemically modifying peptides | THE UNIVERSITY OF DURHAM (GB) | 2018-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10040819-B2 | Chemically modifying peptides | PTMS, DNPEP, NGLY1 | TBXA2R 3538/4885CHRM2 4711/4885CHRM4 4179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.