SCHEMBL20458050

SCHEMBL20458050

CC(=O)Nc1cccc(N(C)C(C)=O)c1

nearest known ligand 0.75

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
HSD17B10 Q99714 2/20 0.56
CYP1A2 P05177 1/20 0.56
POLB P06746 2/20 0.51
NR4A1 P22736 1/20 0.51
RAB9A P51151 1/20 0.51
HTT P42858 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
MTNR1A P48039 1/20 0.48
MTNR1B P49286 1/20 0.48
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
RECQL P46063 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24166779 0.87 MEN1 (0.46) ALDH1A1RAB9ALMNASMN1; SMN2MEN1
SCHEMBL8999455 0.86 ALDH1A1 (0.59) ALDH1A1HSD17B10CYP1A2POLBNR4A1
SCHEMBL24166523 0.85 ALDH1A1 (0.51) ALDH1A1RAB9AL3MBTL1LMNASMN1; SMN2
SCHEMBL8311376 0.84 ALDH1A1 (0.42) ALDH1A1HSD17B10RAB9ALMNASMN1; SMN2
SCHEMBL7824417 0.82 LMNA (0.76) RAB9AHTTLMNASMN1; SMN2MEN1
SCHEMBL26757947 0.82 ALDH1A1 (0.48) ALDH1A1HSD17B10RAB9AHTTL3MBTL1
SCHEMBL12200277 0.81 ALDH1A1 (0.54) ALDH1A1HSD17B10CYP1A2POLBNR4A1
SCHEMBL11809039 0.81 MTNR1A (0.61) ALDH1A1HSD17B10CYP1A2POLBNR4A1
SCHEMBL18513515 0.81 MEN1 (0.49) ALDH1A1HSD17B10CYP1A2POLBNR4A1
SCHEMBL10294637 0.80 POLB (0.57) ALDH1A1HSD17B10CYP1A2POLBNR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10041000-B2 Liquid crystal display device JNC CORPORATION (JP) 2018-08-07 US disclosed