Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20458152 | 0.77 | KDM4E (0.41) | ADORA3NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL20458212 | 0.77 | RAB9A (0.50) | ADORA3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9892835 | 0.75 | ADORA3 (0.67) | ADORA3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL12890452 | 0.71 | SMN1; SMN2 (0.61) | ADORA3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13257168 | 0.69 | ADORA3 (0.68) | ADORA3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13257010 | 0.69 | ADORA3 (0.68) | ADORA3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9790870 | 0.69 | ADORA3 (0.58) | ADORA3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9852227 | 0.66 | NPC1 (0.66) | ADORA3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10509734 | 0.66 | NPC1 (0.66) | ADORA3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9852174 | 0.65 | ADORA3 (0.77) | ADORA3NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |