Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20458153 | 0.77 | ADORA3 (0.49) | TP53HSD17B10HTTNPC1RAB9A | |
| SCHEMBL9892932 | 0.74 | KDM4E (0.53) | KDM4ETP53HSD17B10HTTNPC1 | |
| SCHEMBL20458212 | 0.72 | RAB9A (0.50) | KDM4EHTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16253075 | 0.68 | KDM4E (0.49) | KDM4ETP53HSD17B10HTTNPC1 | |
| SCHEMBL13257156 | 0.68 | KDM4E (0.49) | KDM4ETP53HSD17B10HTTNPC1 | |
| SCHEMBL3266075 | 0.63 | TP53 (0.56) | KDM4ETP53HSD17B10HTTNPC1 | |
| SCHEMBL13842699 | 0.63 | KDM4E (0.63) | KDM4ETP53HSD17B10HTTNPC1 | |
| SCHEMBL20458204 | 0.63 | KDM4E (0.56) | KDM4ETP53HSD17B10HTTNPC1 | |
| SCHEMBL7656935 | 0.63 | KDM4E (0.63) | KDM4ETP53HSD17B10HTTNPC1 | |
| SCHEMBL9892890 | 0.63 | HTT (0.60) | KDM4ETP53HSD17B10HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |