Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22095932 | 0.83 | GPR84 (0.44) | GPR84TSHRCA1CA2CA9 | |
| SCHEMBL28417664 | 0.80 | GPR84 (0.42) | GPR84CA1CA2CA9SLC6A4 | |
| SCHEMBL20371663 | 0.75 | GPR84 (0.53) | GPR84TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL20216311 | 0.74 | GPR84 (0.51) | GPR84TSHRSLC6A4HTR2AHTR2C | |
| SCHEMBL10911463 | 0.74 | LMNA (0.40) | GPR84CA1CA2CA9SLC6A4 | |
| SCHEMBL10262953 | 0.73 | GPR84 (0.58) | GPR84CA1CA2CA9SLC6A4 | |
| SCHEMBL19040082 | 0.73 | GPR84 (0.53) | GPR84SLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL10912848 | 0.72 | CYP51A1 (0.40) | GPR84SLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL29764387 | 0.70 | GPR84 (0.64) | GPR84CA1CA2CA9SLC6A4 | |
| SCHEMBL15826494 | 0.70 | GPR84 (0.64) | GPR84CA1CA2CA9SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2629771-B1 | USE OF PI3K INHIBITORS FOR THE TREATMENT OF OBESITY, STEATOSIS AND AGEING | FUNDACION CENTRO NAC DE INVESTIGACIONES ONCOLOGICAS CARLOS III (ES) | 2018-08-08 | — | — | EP | disclosed |