Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 14/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25514411 | 0.92 | ACHE (0.51) | EPHX1ACHEEPHX2 | |
| SCHEMBL20272872 | 0.87 | EPHX1 (0.42) | EPHX1ACHEEPHX2 | |
| SCHEMBL18699084 | 0.86 | EPHX1 (0.44) | EPHX1ACHE | |
| SCHEMBL21226052 | 0.86 | ACHE (0.39) | EPHX1ACHEEPHX2 | |
| SCHEMBL19227183 | 0.85 | EPHX1 (0.45) | EPHX1ACHE | |
| SCHEMBL19976555 | 0.84 | CASP2 (0.51) | EPHX1EPHX2 | |
| SCHEMBL20272887 | 0.83 | EPHX1 (0.38) | EPHX1ACHEEPHX2 | |
| SCHEMBL15150965 | 0.83 | CHRNB2 (0.41) | ACHE | |
| SCHEMBL19227197 | 0.83 | EPHX1 (0.42) | EPHX1ACHE | |
| SCHEMBL18699101 | 0.82 | EPHX1 (0.42) | EPHX1ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760477-B1 | DI-ALIPHATIC SUBSTITUTED PEGYLATED LIPIDS | ALNYLAM PHARMACEUTICALS INC (US) | 2018-08-08 | — | — | EP | disclosed |