SCHEMBL2045962

SCHEMBL2045962

CCCc1ccc(C2=NCCO2)cc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.49
KCNH2 Q12809 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42
HTR1D P28221 1/20 0.41
LTA4H P09960 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.38
NPC1 O15118 1/20 0.37
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
GFER P55789 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8058665 0.87 HSD17B10 (0.46) NISCHHRH3SMN1; SMN2MAPTRAB9A
SCHEMBL668013 0.86 NISCH (0.46) NISCHKCNH2HRH3LTA4HSMN1; SMN2
SCHEMBL8143013 0.83 KCNH2 (0.42) KCNH2HRH3LTA4H
SCHEMBL132013 0.81 KCNH2 (0.49) KCNH2HRH3LTA4HSMN1; SMN2
SCHEMBL964626 0.81 CTSS (0.41) NISCHHRH3SMN1; SMN2
SCHEMBL28734242 0.80 KCNH2 (0.38) KCNH2HRH3LTA4HSMN1; SMN2
SCHEMBL8365860 0.79 KCNH2 (0.43) KCNH2HRH3LTA4H
SCHEMBL7789783 0.79 KCNH2 (0.43) KCNH2HRH3LTA4HSMN1; SMN2
SCHEMBL27466866 0.79 HRH3 (0.46) KCNH2HRH3LTA4HSMN1; SMN2NPC1
SCHEMBL1814199 0.76 KCNH2 (0.43) NISCHKCNH2HRH3LTA4HSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748543-B2 Polylactic acid film TEIJIN LIMITED (JP) 2014-06-10 US disclosed
US-8030382-B2 Polylactic acid composition TEIJIN LIMITED (JP) 2011-10-04 US disclosed
US-20110224342-A1 POLYLACTIC ACID FILM TEIJIN LIMITED (JP) 2011-09-15 US disclosed
EP-2330148-A1 POLYLACTIC ACID FILM Teijin Limited (JP) 2011-06-08 EP disclosed
US-20100093888-A1 POLYLACTIC ACID COMPOSITION TEIJIN LIMITED (JP) 2010-04-15 US disclosed
EP-2116576-A1 POLYLACTIC ACID COMPOSITION Teijin Limited (JP) 2009-11-11 EP disclosed