Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.45 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20460612 | 0.83 | TP53 (0.50) | TP53HSD17B10KMT2AGAATSHR | |
| SCHEMBL12121137 | 0.83 | TP53 (0.50) | TP53HSD17B10KMT2AGAATSHR | |
| SCHEMBL3343083 | 0.82 | ALDH1A1 (0.51) | TP53HSD17B10KMT2AGAATSHR | |
| SCHEMBL14547912 | 0.82 | TP53 (0.49) | TP53HSD17B10KMT2AGAATSHR | |
| SCHEMBL17993972 | 0.80 | ALDH1A1 (0.46) | TP53GAAHTTMAP2K2MAP2K1 | |
| SCHEMBL10330509 | 0.78 | LMNA (0.58) | HSD17B10KMT2AGAAHPGDSMN1; SMN2 | |
| SCHEMBL14915770 | 0.77 | GAA (0.56) | GAAHTTMAP2K2MAP2K1GPR27 | |
| SCHEMBL24801418 | 0.73 | TP53 (0.63) | TP53HSD17B10KMT2AGAATSHR | |
| SCHEMBL25976159 | 0.72 | GAA (0.78) | HSD17B10KMT2AGAAHPGDMLYCD | |
| SCHEMBL20460549 | 0.72 | MAP2K2 (0.38) | GAAMAP2K2MAP2K1MLYCDGPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10550073-B2 | Benzamide derivative | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2020-02-04 | — | — | US | disclosed |
| EP-3357916-A1 | BENZAMIDE DERIVATIVE | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2018-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550073-B2 | Benzamide derivative | CYP3A5, ABCB1, CYP2D6 | TP53 3242/4885HSD17B10 1894/4885KMT2A 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.