Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 3/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamodial SCHEMBL15557354 | 1.00 | EDNRB (0.41) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Cinnamodial SCHEMBL19454896 | 1.00 | EDNRB (0.41) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Mukaadial SCHEMBL21025699 | 0.80 | EDNRB (0.34) | EDNRBEDNRALMNACYP3A4MAPT | |
| Mukaadial SCHEMBL20462894 | 0.80 | EDNRB (0.34) | EDNRBEDNRALMNACYP3A4MAPT | |
| Capsicodendrin SCHEMBL21026188 | 0.74 | EDNRB (0.39) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| SCHEMBL21025572 | 0.74 | EDNRB (0.37) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Cinnamosmolide SCHEMBL21025897 | 0.70 | NFKB1 (0.43) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Cinnamosmolide SCHEMBL21025700 | 0.70 | NFKB1 (0.43) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| SCHEMBL21025698 | 0.70 | EDNRB (0.44) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Cinnamosmolide SCHEMBL21025571 | 0.70 | NFKB1 (0.43) | EDNRBEDNRANFKB1STAT1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018142288-A1 | MUKAADIAL ACETATE ISOLATED FROM WARBURGIA SALUTARIS AND THE USE THEREOF AS AN ANTIMALARIAL | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2018-08-09 | — | — | WO | disclosed |