Cinnamosmolide

Cinnamosmolide

SCHEMBL21025897

CC(=O)O[C@@H]1C=C2C(=O)OC[C@]2(O)[C@@]2(C)CCCC(C)(C)[C@H]12

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NFKB1 P19838 3/20 0.43
▸ STAT1 P42224 2/20 0.43
▸ NFKB2 Q00653 2/20 0.43
▸ RELA Q04206 2/20 0.43
▸ EDNRB P24530 3/20 0.43
▸ EDNRA P25101 2/20 0.40
▸ CASP1 P29466 1/20 0.36
▸ CASP3 P42574 1/20 0.36
▸ MAPK1 P28482 4/20 0.31
▸ CYP3A4 P08684 3/20 0.31
▸ TSHR P16473 2/20 0.31
▸ GMNN O75496 1/20 0.31
▸ BLM P54132 1/20 0.31
▸ PMP22 Q01453 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ CYP2D6 P10635 1/20 0.31
▸ HIF1A Q16665 1/20 0.31
▸ NR1I2 O75469 1/20 0.31
▸ CHRM2 P08172 1/20 0.31
▸ ABCB1 P08183 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinnamosmolide SCHEMBL21025700 1.00 NFKB1 (0.43) NFKB1STAT1NFKB2RELAEDNRB
Cinnamosmolide SCHEMBL21025571 1.00 NFKB1 (0.43) NFKB1STAT1NFKB2RELAEDNRB
Cinnamosmolide SCHEMBL15557098 1.00 NFKB1 (0.43) NFKB1STAT1NFKB2RELAEDNRB
Pereniporin B SCHEMBL21025895 0.81 NFKB1 (0.34) NFKB1STAT1NFKB2RELAEDNRB
Cinnamodial SCHEMBL15557354 0.70 EDNRB (0.41) NFKB1STAT1NFKB2RELAEDNRB
Cinnamodial SCHEMBL20462860 0.70 EDNRB (0.41) NFKB1STAT1NFKB2RELAEDNRB
SCHEMBL21025894 0.69 EDNRB (0.47) NFKB1STAT1NFKB2RELAEDNRB
SCHEMBL21025698 0.68 EDNRB (0.44) NFKB1STAT1NFKB2RELAEDNRB
Ugandensolide SCHEMBL21025899 0.60 MAPK1 (0.31) NFKB1STAT1NFKB2RELAEDNRB
SCHEMBL14982984 0.59 CYP3A4 (0.37) NFKB1NFKB2RELAMAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12478091-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-11-25 — — US claimed
US-11946083-B2 Method for the microbial production of specific natural capsaicinoids CONAGEN INC. (US) 2024-04-02 — — US claimed
US-20230012268-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATION WITH STEROIDS AND A MODULATOR BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) 2023-01-12 — — US claimed
US-20220403427-A1 METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS CONAGEN INC. (US) 2022-12-22 — — US claimed
EP-4072558-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATION WITH STEROIDS AND A MODULATOR Buzzelet Development And Technologies Ltd (IL) 2022-10-19 — — EP claimed
US-20220233463-A1 LOCAL ANESTHETIC COMPRISING A TRP CHANNEL MODULATOR BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) 2022-07-28 — — US claimed
EP-4017486-A1 COMPOSITONS FOR THE TREATMENT OF A CONDITION CHARACTERIZED BY ANANDAMIDE DEFICIENCY AND USES THEREOF Buzzelet Development And Technologies Ltd (IL) 2022-06-29 — — EP claimed
US-20220168246-A1 COMPOSITONS FOR THE TREATMENT OF A CONDITION CHARACTERIZED BY ANANDAMIDE DEFICIENCY AND USES THEREOF BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) 2022-06-02 — — US claimed
EP-3968970-A1 LOCAL ANESTHETIC COMPRISING A TRP CHANNEL MODULATOR Buzzelet Development And Technologies Ltd (IL) 2022-03-23 — — EP claimed
EP-4683527-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2026-01-28 — — EP disclosed
US-20250388533-A1 PRODRUGS OF PHENOLIC TRPV1 AGONISTS CONCENTRIC ANALGESICS INC (US) 2025-12-25 — — US disclosed
US-12497381-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-12-16 — — US disclosed
US-12478091-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-11-25 — — US disclosed
US-20250312298-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF PAIN USING CAPSAICIN ANKURA TRUST COMPANY, LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT 2025-10-09 — — US disclosed
EP-4017486-A1 COMPOSITONS FOR THE TREATMENT OF A CONDITION CHARACTERIZED BY ANANDAMIDE DEFICIENCY AND USES THEREOF Buzzelet Development And Technologies Ltd (IL) 2022-06-29 — — EP disclosed
US-20220168246-A1 COMPOSITONS FOR THE TREATMENT OF A CONDITION CHARACTERIZED BY ANANDAMIDE DEFICIENCY AND USES THEREOF BUZZELET DEVELOPMENT AND TECHNOLOGIES LTD (IL) 2022-06-02 — — US disclosed
US-11344516-B2 Stable aqueous capsaicin injectable formulations and medical uses thereof CENTREXION THERAPEUTICS CORPORATION (US) 2022-05-31 — — US disclosed
US-20220112165-A1 PEGYLATED PRODRUGS OF PHENOLIC TRPV1 AGONISTS Concentric Analgesics, Inc. 2022-04-14 — — US disclosed
EP-3968970-A1 LOCAL ANESTHETIC COMPRISING A TRP CHANNEL MODULATOR Buzzelet Development And Technologies Ltd (IL) 2022-03-23 — — EP disclosed
US-20190150437-A1 USE OF SESQUITERPENES AND THEIR ANALOGS AS GREEN INSECTICIDES FOR CONTROLLING DISEASE VECTORS AND PLANT PESTS OHIO STATE INNOVATION FOUNDATION 2019-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312298-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF PAIN USING CAPSAICIN TRPV1, TRPV4, TRPV5 NFKB1 1524/4885STAT1 2827/4885NFKB2 2058/4885
US-20250388533-A1 PRODRUGS OF PHENOLIC TRPV1 AGONISTS TRPV1, TRPV3, TRPV4 NFKB1 3181/4885STAT1 4059/4885NFKB2 2932/4885
US-20190150437-A1 USE OF SESQUITERPENES AND THEIR ANALOGS AS GREEN INSECTICIDES FOR CONTROLLING DISEASE VECTORS AND PLANT PESTS NOTUM, DDT, CYP51A1 NFKB1 3371/4885STAT1 3609/4885NFKB2 3832/4885
US-11344516-B2 Stable aqueous capsaicin injectable formulations and medical uses thereof IL15, TRPV1, TRPV5 NFKB1 163/4885STAT1 2310/4885NFKB2 1103/4885
US-20220112165-A1 PEGYLATED PRODRUGS OF PHENOLIC TRPV1 AGONISTS TRPV1, TRPV4, TRPV3 NFKB1 1822/4885STAT1 1947/4885NFKB2 1750/4885
US-20220403427-A1 METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS TRPV1, CYP51A1, NAAA NFKB1 2811/4885STAT1 4394/4885NFKB2 3019/4885
US-12497381-B2 Vaporizable alkaloid compositions and methods of use thereof CHRM5, NNMT, CHRM1 NFKB1 4606/4885STAT1 4339/4885NFKB2 4806/4885
US-11946083-B2 Method for the microbial production of specific natural capsaicinoids TRPV1, CYP51A1, NAAA NFKB1 2811/4885STAT1 4394/4885NFKB2 3019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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