Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 3/20 | 0.34 |
| ▸ | EDNRA | P25101 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mukaadial SCHEMBL20462894 | 1.00 | EDNRB (0.34) | EDNRBEDNRAMAPTCYP3A4RECQL | |
| Cinnamodial SCHEMBL15557354 | 0.80 | EDNRB (0.41) | EDNRBEDNRAMAPTCYP3A4LMNA | |
| Cinnamodial SCHEMBL20462860 | 0.80 | EDNRB (0.41) | EDNRBEDNRAMAPTCYP3A4LMNA | |
| Warburganal SCHEMBL13855683 | 0.73 | CHRNB2 (0.45) | MAPTIDO1TRPA1ALDH1A1CHRNB2 | |
| Warburganal SCHEMBL4244667 | 0.73 | CHRNB2 (0.45) | MAPTIDO1TRPA1ALDH1A1CHRNB2 | |
| Warburganal SCHEMBL288951 | 0.73 | CHRNB2 (0.45) | MAPTIDO1TRPA1ALDH1A1CHRNB2 | |
| SCHEMBL11130748 | 0.67 | PDE4D (0.45) | MAPTCYP3A4TRPA1ALDH1A1LMNA | |
| Pereniporin B SCHEMBL21025895 | 0.65 | NFKB1 (0.34) | EDNRBEDNRAMAPTCYP3A4RECQL | |
| SCHEMBL11451547 | 0.61 | TRPA1 (0.34) | MAPTCYP3A4RECQLTRPA1 | |
| SCHEMBL14882179 | 0.61 | TRPA1 (0.34) | MAPTCYP3A4RECQLTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190150437-A1 | USE OF SESQUITERPENES AND THEIR ANALOGS AS GREEN INSECTICIDES FOR CONTROLLING DISEASE VECTORS AND PLANT PESTS | OHIO STATE INNOVATION FOUNDATION | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190150437-A1 | USE OF SESQUITERPENES AND THEIR ANALOGS AS GREEN INSECTICIDES FOR CONTROLLING DISEASE VECTORS AND PLANT PESTS | NOTUM, DDT, CYP51A1 | EDNRB 4560/4885EDNRA 3352/4885MAPT 2412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.